Tuesday, March 3, 2015

The Blood Group of parents (both father & mother) is A+. Their female child blood group is A-. Is this possible?

If the parents both carry the recessive gene form (allele) for the Rh gene then yes it is possible.


If dad was AA+- or Ao+- he could make a sperm cell that contained an A-. (possible sperm cells A+, A- in the first case & A+, A-, o+, o- in the second).


If mom also had either of the above genotypes she could produce an egg cell A- or o- and a baby with the phenotype (body) type A blood, Rh negative.


To set up the punnett squares:


dad AA+- with mom AA+-  (dad always goes on top of punnett suare)


A+     A-


A+


A-


you get a 1 in 4 chance of a AA-- (type A negative baby)



dad Ao+- with mom AA+-


A+     A-     o+     o-


A+


A-


you also get a 2 in 8 (1in4) chance of a type A negative child



dad Ao+- with mom Ao+-


A+     A-     o+     o-


A+


A-


o+


o-


you get a 3 of 16 chance of a type A negative child


(Even a type AB+- father or mother could produce sperm and egg cells capable of making a Type A negative child.)

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